Exercise and Physical Functioning in Osteoarthritis: by Joost Dekker (auth.), Joost Dekker (eds.)

By Joost Dekker (auth.), Joost Dekker (eds.)

Osteoarthritis (OA) is without doubt one of the best 10 of such a lot disabling ailments within the Western global. it's the significant reason behind discomfort and incapacity one of the aged. This publication offers a contextual overview of modern examine on neuromuscular elements and behavioral possibility elements for useful decline in OA, with a different emphasis on explanatory mechanisms. additionally, the ebook discusses leading edge ways to workout and actual job in OA, derived from learn on behavioral and neuromuscular hazard elements for sensible decline in OA. contemporary study has proven that neuromuscular components (such as muscle power, joint laxity) and behavioral components (such as avoidance of job, depressed temper) expect ache and incapacity in OA. in addition, workout and actual job are one of the dominant interventions aiming at lowering discomfort and incapacity, and cutting edge interventions concentrating on neuromuscular and behavioral interventions were lately built. This learn has been released as separate papers, with the end result that the sphere is short of an integrative contextual overview that places the study into theoretical perspective.

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Altman R, Alarcon G, Appelrouth D, Bloch D, Borenstein D, Brandt K et al (1991) The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hip. Arthritis Rheum 34(5):505–514 54. Peat G, Thomas E, Duncan R, Wood L, Hay E, Croft P (2006) Clinical classification criteria for knee osteoarthritis: performance in the general population and primary care. Ann Rheum Dis 65(10):1363–1367 55. Knoop J, van der Leeden LM, Thorstensson CA, Roorda LD, Lems WF, Knol DL et al (2011) Identification of phenotypes with different clinical outcomes in knee osteoarthritis: data from the osteoarthritis initiative.

Ann Rheum Dis 55(9):685–688 17. Ledingham J, Dawson S, Preston B, Milligan G, Doherty M (1993) Radiographic progression of hospital referred osteoarthritis of the hip. Ann Rheum Dis 52(4):263–267 18. Kinds MB, Marijnissen AC, Vincken KL, Viergever MA, Drossaers-Bakker KW, Bijlsma JW et al (2012) Evaluation of separate quantitative radiographic features adds to the prediction of incident radiographic osteoarthritis in individuals with recent onset of knee pain: 5-year follow-up in the CHECK cohort.

It was shown to be superior to placebo in reducing pain, although the effect size is small. Acetaminophen has no significant effect on stiffness or functioning in patients with symptomatic knee OA. Acetaminophen in recommended dosages is safe. However, upon chronic use in high dosages (>3 g/day), it may have upper gastrointestinal side effects, lead to mild impairment in renal function, and hypertension [2, 3]. It is also important to realize that it may lead to fatal liver damage when toxic dosages are used, for instance in tentamen suicidi.

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