Bioaccumulation - New Aspects and Developments by B. Beek

By B. Beek

The bioaccumulation of endocrine disruptors, chronic natural chemical compounds and different compounds of excessive environmental effect has develop into of accelerating curiosity in most modern environmental study, hazard research and toxicology. This quantity supplies an updated evaluation and introduces the reader to the recent proposal of "internal influence focus" linking bioaccumulation and biomagnification within the meals chain to ecotoxicology and danger overview.

Show description

Read or Download Bioaccumulation - New Aspects and Developments PDF

Similar environmental books

System Identification, Environmental Modelling, and Control System Design

This publication is devoted to Prof. Peter younger on his seventieth birthday. Professor younger has been a pioneer in structures and regulate, and during the last forty five years he has encouraged many advancements during this box. This quantity includes a set of contributions through top specialists in method id, time-series research, environmetric modelling and keep an eye on process layout – glossy study in subject matters that mirror vital components of curiosity in Professor Young’s study profession.

Environmental Monitoring and Reporting by Enterprises: Eastern Europe, Caucasas and Central Asia

The current booklet includes the information for Strengthening Environmental tracking and Reporting by way of businesses in jap Europe, Caucasus and crucial Asia. it really is geared toward officers and specialists operating for presidency our bodies liable for environmental coverage, environmental tracking and compliance tracking, and statistical companies, in addition to for company administration and environmental electorate firms.

Additional resources for Bioaccumulation - New Aspects and Developments

Example text

It is important to note that some synthetic estrogens, such as diethylstilbestrol (DES), moxestrol, and 11b-chloromethyl estradiol show 10 times more estrogenic activity than 17b-estradiol in the E-SCREEN assay [136]. Ethinylestradiol has the same estrogenic activity as 17b-estradiol, whereas the activity of the synthetic EDCs is by some orders of magnitude lower [136]. In this context it is important to note that most, if not all, efflu- Bioaccumulation and Occurrence of Endocrine-Disrupting Chemicals (EDCs) 37 ents of sewage treatment plants [145 b] and some rivers [145 c] in the United Kingdom are estrogenic to fish.

232c]. Measured by Nakagawa et al. [232d]. BCF value of 14C-3,4-DCA in three-spined stickleback [232e]. Worst-case BCFL value for fish predicted from the log Kow value if no metabolism occurs or is negligible. J. Geyer et al. Recently, it was found by Kelce et al. [125a] that the persistent p,p¢-DDT metabolite p,p¢-DDE is a potent androgen receptor antagonist. This compound is highly hydrophobic and has a very high bioconcentration potential. Furthermore, it is important to note that also estrogens, such as estradiol, diethylstilbestrol, Kepone, o,p¢-DDT, and methoxychlor can bind also to the androgen receptor [125b].

They found also no synergism. It is important to note that very recently McLachlan et al. [145 a] have just formally withdrawn their report. In his laboratory the coworkers have conducted experiments duplicating the conditions of their earlier work, but were unable to replicate their original results. The natural female steroid hormone with the greatest estrogenic activity is 17ß-estradiol. It is important to note that some synthetic estrogens, such as diethylstilbestrol (DES), moxestrol, and 11b-chloromethyl estradiol show 10 times more estrogenic activity than 17b-estradiol in the E-SCREEN assay [136].

Download PDF sample

Rated 4.44 of 5 – based on 36 votes